Etiology and Serological Diagnosis Of Swine Atrophic Rhinitis

It is urgent to ascertain the etiological agent of the swine atrophic rhinitis (AR) for the diagnosis and treatment of this disease. Therefore, many etiological theories have been offered up to the present day, and after all, it has been elucidated that AR is a transmissible disease of the swine: Since 1963, Switzer and his co-workers' >.2 >>,3> have presented the agency theory of Alealiyenes (Bordetellci) bronehisepticus in America, but it seems that other foreign researchers have not confirmed it thoroughly yet. In these infectious experiments, the workers have made efforts to use the possible diseasefree hard, but it seems that there has been no explorative paper concerning individual etiological agent of AR used hysterectomy produced colostrum deprived (HPCD) pigs. Thel'efore, Shimizu et a l.i undertook to see if Ale. bronehiseptieus is the causative agent of AR for HPCD pigs. After inoculation of this bacterium, all 6 HPCD pigs revealed typical turbinate atrophy macroscopically and microscopically. This fact certifies that Ale. bronchisepticus is one of the important etiological agents of the swine atrophic rhinitis. It seems that there has been no established serological diagnosis of AR up to date. In 1969, Nakagawa et aJ. > evaluated diagnostic technique of the tube agglutination test for broncho-pneumonia caused by Ale. bronchisepticus in guinea pigs. Kang et al. (1970) > applied that technique to the diagnosis of AR with minor change. Shimizu et al. (1970°> modified this technique still more. And so, the production of agglutinin at an early stage after infection was certified.